Harry speaks of his grief and growing up after the death of his mother Princess Diana when he was just 12, his use of cocaine and other drugs to cope, how he killed 25 Taliban fighters while serving as a soldier in Afghanistan, and even how he lost his virginity.
He also reveals a heated row with William, the heir to the throne, saying his brother knocked him over, and how they had both begged his father not to marry Camilla, who he wed in 2005 and is now the queen consort.
In TV interviews ahead of the book launch, Harry has doubled down on his accusations that some royals, including Camilla and William, leaked stories to tabloid papers which had damaged either him or his wife Meghan in order to protect themselves or enhance their reputations.
"I think she (his mother Diana) would be heartbroken about the fact that William, his office, were part of these stories," he told Good Morning America (GMA).
In another interview with CBS show 60 minutes, he said Camilla had been a tabloid "villain" and needed to rehabilitate her image, which made her "dangerous".
"I don't regard her as an evil stepmother. I see someone who married into this institution and has done everything that she can to, you know, improve her reputation and her own image," he told GMA.
While Harry's revelations have dominated the headlines in the British media over the last week, the interest in his disclosures is far from universal.
"I was not planning to (read the book) as it so happens, or certainly not as a early priority," business minister Grant Shapps told Times Radio on Tuesday. "I've got one or two other things to do."
