"I think she (his mother Diana) would be heartbroken about the fact that William, his office, were part of these stories," he told Good Morning America (GMA).
In another interview with CBS show 60 minutes, he said Camilla had been a tabloid "villain" and needed to rehabilitate her image, which made her "dangerous".
"I don't regard her as an evil stepmother. I see someone who married into this institution and has done everything that she can to, you know, improve her reputation and her own image," he told GMA.
While Harry's revelations have dominated the headlines in the British media over the last week, the interest in his disclosures is far from universal.
"I was not planning to (read the book) as it so happens, or certainly not as a early priority," business minister Grant Shapps told Times Radio on Tuesday. "I've got one or two other things to do."
