At the center of the legal case is a December 2018 opinion piece by Heard in the Washington Post. The article never mentioned Depp by name, but his lawyer told jurors it was clear that Heard was referring to him.
Depp, once among Hollywood's biggest stars, said Heard's allegations cost him "everything." A new "Pirates" movie was put on hold, and Depp was replaced in the "Fantastic Beasts" film franchise, a "Harry Potter" spinoff.
Heard's attorneys have argued that she told the truth and her opinion was protected free speech under the U.S. Constitution's First Amendment. They said she also lost work opportunities in Hollywood because of Depp's accusations.
Depp lost a libel case less than two years ago against the Sun, a British tabloid that labeled him a "wife-beater." A London High Court judge ruled that he had repeatedly assaulted Heard.
Depp's lawyers filed the U.S. case in Fairfax County, Virginia, because the Washington Post is printed there. The newspaper is not a defendant.
Both sides have claimed damage to their Hollywood careers.
Heard's legal team presented an entertainment industry expert who estimated that the actress has suffered $45-50 million in lost film and TV roles and endorsements.
An industry expert hired by Depp's side said the actor has lost millions because of the abuse accusations, including a $22.5 million payday for a sixth installment of "Pirates".