"More than 100 combat, reconnaissance and attack drones belonging to the army are kept for operations in this base located in the heart of the Zagros mountains," the report said.
Bagheri, quoted by the official news agency IRNA, described the site as a "safe operational base for strategic drones".
"We never underestimate threats, we never assume the enemy is asleep, and we are constantly alert and vigilant," he added.
Mousavi told state television the base was located "several hundred metres (yards) underground", without giving further details.
State TV said the flagship of the fleet was the "Kaman-22", a drone equipped with missiles and able to fly at least 2,000 kilometres (1,245 miles).
The US Treasury slapped sanctions on the drone programme of Iran's Islamic Revolutionary Guard Corps in October last year.
It accused the Guards of being behind a September 2019 drone strike on a Saudi oil refinery, as well as a July 2021 drone attack on a commercial ship off the coast of Oman that killed two crewmen.
Iran denied the charges.
