By that time, Depp had "done all the drugs I was aware of," he said. He said he became addicted to opiates after he was injured on the set of the fourth "Pirates" film but recovered from that dependency.
Depp said Heard "grossly embellished" his substance use. "A lot of it is just plainly false," he said. "I think it was an easy target for her to hit."
Heard watched the testimony with little expression while Depp spoke, occasionally tilting her head or jotting notes.
Less than two years ago, Depp lost a libel case against The Sun, a British tabloid that labeled him a "wife beater." A London High Court judge ruled he had repeatedly assaulted Heard and put her in fear for her life.
In the U.S. case, Depp and Heard both submitted long lists of potential witnesses they may call, including Heard's ex-boyfriend and Tesla Chief Executive Elon Musk and actor James Franco.
Depp's lawyers have said they filed the case in Fairfax County, outside the District of Columbia, because the Washington Post is printed at a facility there. The Washington Post is not a defendant in the case.