COVID-19 vaccine tested on humans shows early promise

US biotech firm Moderna said Tuesday it would enter the final stage of human trials for its COVID-19 vaccine on July 27, to test how well it protects people in the real world. The announcement came as the results from an earlier trial, that intended to prove the vaccine was safe and triggered antibody production, were published.

A Massachusetts-based biotech company has been testing a possible vaccine against the novel which is showing early signs of success.

announced an estimated start date for phase 3 trials, its final phase of testing.

The trial involved 45 volunteers aged 18 to 55 who received one of three dosage levels of the vaccine, which was given in two injections about a month apart.

Researchers measured virus-recognizing antibodies in all participants and detected levels similar to or higher than those found in the blood of people who have recovered from COVID-19.

It is not clear how long the immune response will protect against COVID-19, but volunteers will be monitored for a year to find out. Some participants experienced mild side effects such as fatigue, chills, headache and weakness.

Moderna's vaccine, which is being co-developed with the US National Institute of Allergy and Infectious Diseases (NIAID), began safety testing in humans in March. Phase 3 tests will begin on July 27 and will involve 30,000 people, according to a May 18 press release.

Half of the participants will be a control group who will receive placebos. This large clinical trial is expected to be completed by late October.

More than 100 vaccines worldwide are being studied for use against COVID-19, and at least eight of these have already progressed to human studies.


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