5-year-old boy dies of Ebola as Uganda cases rise to 3

A 5-year-old boy has died of in , the said on Wednesday, shortly after he was confirmed to be the first cross-border case from the current in neighbouring Congo. "The young patient ... died last night," WHO Uganda said on Twitter, adding that two more cases of the virus had been confirmed in the country.

A 5-year-old boy vomiting blood became the first cross-border victim of in the current on Wednesday, while two more people in tested positive for the highly contagious disease that has killed nearly 1,400 in Congo.

The boy, part of a Congolese family who crossed into Uganda earlier in the week, died overnight, the said. Ugandan authorities said the two new cases are his 3-year-old brother and 50-year-old grandmother, who have been isolated at a hospital near the Congo border. Uganda now has three confirmed Ebola cases.

Authorities are trying to determine how the family, exposed to the virus via a sick relative in Congo, managed to cross a border where health officials have been screening millions of travelers for months.

This has become the second-deadliest Ebola outbreak in history since the first cases were declared in August. A WHO expert committee has been alerted for a possible meeting on whether to declare a global health emergency now that the outbreak has crossed the border, a spokesman said.

Experts have long feared Ebola could spread to neighboring countries because of rebel attacks and community resistance hampering virus containment work in eastern Congo, one of the world's most turbulent regions. The virus can spread quickly via close contact with bodily fluids of those infected and can be fatal in up to 90% of cases.

Congo's health ministry said a dozen members of the boy's family had showed symptoms of Ebola. They were not placed in isolation and instead were told to remain where they were staying until transport was found to an Ebola treatment unit in Beni, Dr. Dominique Kabongo, coordinator of Ebola response teams in Kasindi, told the AP.

Instead half of the family quietly crossed into Uganda, while five of the others have tested positive for Ebola since being taken to Beni, Congo's health ministry said.

"Many people are evading customs and using small footpaths and it is difficult for us to follow the contacts," Kabongo said.

The family likely did not pass through official border points, where health workers screen all travelers for a high temperature and isolate those who show signs of illness.

In Uganda, where authorities had been alerted by Congolese colleagues, the boy received treatment while relatives were isolated and tested. The boy's uncle is now among seven suspected Ebola cases in Uganda, Health Minister Jane Aceng said, adding that authorities on both sides of the border would do their best to close unauthorized crossings.

Ugandan health teams "are not panicking," Henry Mwebesa, a physician and the national director of health services, told The Associated Press. He cited the East African nation's experience battling previous outbreaks of Ebola and other hemorrhagic fevers.

"We have all the contingencies to contain this case," Mwebesa said. "It is not going to go beyond" the patient's family. The child's mother, who is married to a Ugandan, knew where to cross the border unofficially, he added.

In the border area where the family is thought to have crossed, surveillance teams patrolled the Ugandan side on Wednesday. Some footpaths, however, remained unguarded. Some people wade across the shallow Lubiriha River instead of using a bridge, to avoid being stopped by officials.

The "stubbornness of Congolese here" is a challenge in screening, a Ugandan Red Cross official, Francis Tumwine, told the AP at one border crossing last week. "They have failed to understand that Ebola is there, they think that it is witchcraft which is killing them."

A Congolese trader, Muhindo Kaongezekela, added: "We are not sure if there's Ebola in Congo. In Congo, if they find you with a headache, they take you to the hospital and later say they died of Ebola."

Uganda is more stable than eastern Congo, and for the first time an experimental but effective Ebola vaccine is being widely used, with more than 130,000 doses distributed. Uganda has vaccinated nearly 4,700 health workers, and WHO is shipping in another 3,500 vaccine doses this week for health workers and close contacts of those infected.

But Ebola has been especially feared in Uganda, where multiple outbreaks have occurred over the years. An outbreak in the north in 2000 infected 425 people and killed more than half of them.

The WHO expert committee has twice decided that the current outbreak, while of "deep concern," is not yet a global health emergency .

But international spread is one of the major criteria the United Nations agency considers before such a declaration. Millions of travelers along Congo's border with Uganda and Rwanda have been screened for Ebola since the outbreak began. WHO has advised against travel restrictions.

The news of a first cross-border case is "tragic but unfortunately not surprising," said Dr. Jeremy Farrar with the Wellcome Trust, which is funding vaccine research in this outbreak.

While Uganda is well-prepared with established surveillance, he added, "we can expect and should plan for more cases in (Congo) and neighboring countries. This epidemic is in a truly frightening phase and shows no sign of stopping anytime soon."

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